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Spastic conditions and research

Spinal cord trauma is one of the most devastating injuries that can be encountered, and many New York residents suffer from the debilitating and long-term effects of such an injury. Research into the mechanism underlying spinal trauma and associated motor conditions have made major strides forward, and it is now believed that the trauma-related chemical feedback loop that causes spasticity has been isolated and identified.

Spasticity occurs when a muscle becomes uncontrollably stimulated, spasming and contracting without the volition of the injured individual. This condition is both debilitating and degenerative, and there is at present no satisfactory treatment for it. The researchers have tracked the condition to a malfunction in the sodium channels of neurons. A signaling problem with the channels causes the neurons to excite unpredictably.

There are already drugs being tested for use on this, and the future looks bright for people suffering from spasticity. Prospective new pharmaceuticals like riluzole and calpain inhibitors have been shown to be effective in animals, and riluzole is already in use as a treatment for a separate condition. This means that human trials may begin quickly, and relief may be on the way for people who suffer from the condition.

A spinal cord injury can be incurred in several ways, and one is a motor vehicle accident. These types of injuries can be life-altering events, preventing a victim from returning to gainful employment. If such an injury was caused by the negligence of another party, such as an impaired or distracted driver, then legal counsel could be of assistance in seeking compensation for the losses that have been sustained.

Source: Medical Xpress, "Two Potential Therapeutic Avenues for Spasticity", March 17, 2016

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